« Back
Home /
CaV1.3 antagonist-1

CaV1.3 antagonist-1

Item no.	HY-134542-5mg
Manufacturer	MedChem Express
CASRN	1391385-57-1
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.38
Formula	C17H19ClN2O3
Citations	[1]Soosung Kang, et al. CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nat Commun. 2012;3:1146.
Smiles	O=C1N(C2CCCC2)C(CC(N1CCC3=CC=CC(Cl)=C3)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Calcium Channel
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	334.80
Product Description	CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Isoform	L-type calcium channel
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-134542-5mg-safety-datasheet.pdf