Comparison

CaV1.3 antagonist-1 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 5mg
Item no. HY-134542-5mg
CASRN 1391385-57-1
Available
Product Description
CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research.
StorageTemperature
4°C, protect from light; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Applications
Neuroscience-Neurodegeneration
Formula
C17H19ClN2O3
References
[1].Soosung Kang, et al. CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nat Commun. 2012; 3:1146.
MolecularWeight
334.8
Research Area
Neurological Disease
Solubility
DMSO : 100 mg/mL (298.69 mM; Need ultrasonic)
Target
Calcium Channel
Isoform
CaV1.3
Pathway
Membrane Transporter/Ion Channel; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 5mg
Available: In stock
available

Delivery expected until 4/13/2023 

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