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CaV1.3 antagonist-1

CaV1.3 antagonist-1

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-134542-5mg
CASRN	1391385-57-1
Available
Product Description	CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research.
StorageTemperature	4°C, protect from light; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Applications	Neuroscience-Neurodegeneration
Formula	C17H19ClN2O3
References	[1].Soosung Kang, et al. CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nat Commun. 2012; 3:1146.
MolecularWeight	334.8
Research Area	Neurological Disease
Solubility	DMSO : 100 mg/mL (298.69 mM; Need ultrasonic)
Target	Calcium Channel
Isoform	CaV1.3
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling

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Amount: 5mg

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Delivery expected until 4/13/2023

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