HPN-01

Item no.	HY-135366-50mg
Manufacturer	MedChem Express
CASRN	928655-63-4
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.61
Citations	[1]Christopher JA, et al. The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-alpha and IKK-beta kinases. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3972-7.\|[2]Ke Li, et al. Amino-aryl-benzamide compounds and methods of use thereof.WO2018204775A1.
Smiles	O=C(C1=C(N)C(C2=CC=C(S(=O)(N)=O)C=C2)=CC(C3=CC=C(Cl)C=C3)=C1)N
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	IKK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	401.87
Product Description	HPN-01 is a potent and selective IKK inhibitor, with pIC50 values of 6.4, 7.0 and [1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	NF-κB
Isoform	IKK-α; IKK-β; IKKε
Clinical information	Phase 1

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HY-135366-50mg-safety-datasheet.pdf