Comparison

6-Hydroxybenzbromarone European Partner

Item no. HY-135774-25mg
Manufacturer MedChem Express
CASRN 152831-00-0
Amount 25 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category
Type Inhibitor
Specific against other
Purity 99.86
Formula C17H12Br2O4
Citations [1]Pandey RN, et al. Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.PLoS One. 2013 Dec 18;8(12):e84582.
Smiles O=C(C1=CC(Br)=C(O)C(Br)=C1)C2=C(CC)OC3=CC(O)=CC=C23
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Neuroscience-Neuromodulation
Manufacturer - Targets
Drug Metabolite; Phosphatase
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
440.08
Product Description
6-Hydroxybenzbromarone is the?major metabolite of Benzbromarone with a longer half-life and greater pharmacological potency than the parent compound.?6-Hydroxybenzbromarone is a?protein Eyes Absent 3 (EYA3) inhibitor with an IC50 value of 21.5 μM.?6-Hydroxybenzbromarone is an?anti-angiogenic agent, ?has strong?inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting[1].
Manufacturer - Research Area
Cardiovascular Disease
Solubility
DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Metabolic Enzyme/Protease
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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