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DGK-IN-1

DGK-IN-1

Item no.	HY-135898-1ea
Manufacturer	MedChem Express
CASRN	2407892-34-4
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.67
Citations	[1]Velaparthi U, et al. Preparation of substituted naphthyridinone compounds useful as T cell activators. WO2020006018A1. World Intellectual Property Organization. A1 2020-01-02.
Smiles	N#CC1=NC2=C(N(C)C(C=C2N3[C@@H](C)CN(C(C4=CC=C(Cl)C=C4)C5=CC=C(Cl)C=C5)[C@H](C)C3)=O)C=C1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	DGK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	532.46
Product Description	DGK-IN-1 is a DGK inhibitor (DGKa/DGKz IC50: 0.65/0.25 μM). DGK-IN-1 is a T cell activator that can be used in cancer and viral infection research[1].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO: 5 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-135898-1ea-safety-datasheet.pdf