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Xeruborbactam (disodium)

Xeruborbactam (disodium)

Item no.	HY-136072-50mg
Manufacturer	MedChem Express
CASRN	2170848-99-2
Amount	50 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.92
Citations	[1]Lomovskaya O, et al, The Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Antimicrob Agents Chemother. 2020 Mar 30. pii: AAC.00552-20.\|[2]Hecker SJ, Reddy KR, Lomovskaya O, et al. Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases. J Med Chem. 2020;63(14):7491-7507.
Smiles	O[B-](O1)(O)[C@@H]2C[C@@H]2C3=C1C(C(O[Na])=O)=C(C=C3)F.[Na+]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	QPX7728 (disodium)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	283.96
Product Description	Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range[1].
Manufacturer - Research Area	Infection
Solubility	DMSO: 100 mg/mL (ultrasonic)\|H2O: 76.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	Phase 1

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HY-136072-50mg-safety-datasheet.pdf