Comparison

Deruxtecan European Partner

Item no. HY-13631E-50mg
Manufacturer MedChem Express
CASRN 1599440-13-7
Amount 50 mg
Quantity options 100 mg 10 mMx1 mL 10 mg 1 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.94
Formula C52H56FN9O13
Citations [1]NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1.
[2]Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
Smiles O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C48)=O)=O)=O)=O)=O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias MC-GGFG-DXD
Shipping condition Cool pack
Available
Manufacturer - Type
ADC Related
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Drug-Linker Conjugates for ADC
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Product Description
Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a
maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
Manufacturer - Research Area
Cancer
Solubility
DMF : 100 mg/mL (ultrasonic)|DMSO : 73.33 mg/mL (ultrasonic)
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related
Isoform
Camptothecins
Clinical information
Phase 4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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