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Orexin receptor antagonist 2

Orexin receptor antagonist 2

Item no.	HY-136922-10mg
Manufacturer	MedChem Express
CASRN	1457940-75-8
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Metabolism Glucose Homeostasis Regulation of Appetite Obesity Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.08
Citations	[1]Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia. J Med Chem. 2013;56(19):7590-7607.
Smiles	O=C1N(CC2=CNC3=C2C=C(OC)C=C3)CCCC14CCN(C5=NC(C)=CC(C)=N5)CC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1457940-75-8
Similar products	1457940-75-8
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Orexin Receptor (OX Receptor)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	433.55
Product Description	Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	No Development Reported

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HY-136922-10mg-safety-datasheet.pdf