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Dimethindene (maleate)

Dimethindene (maleate)

Item no.	HY-13710A-5mg
Manufacturer	MedChem Express
CASRN	3614-69-5
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.72
Formula	C24H28N2O4
Citations	[1]Weller K, et, al. Mast cells are required for normal healing of skin wounds in mice. FASEB J. 2006 Nov;20(13):2366-8.\|[2]Sakuta H. Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102.\|[3]Towart R, et al. Investigation of the antihistaminic action of dimethindene maleate (Fenistil) and its optical isomers. Agents Actions Suppl. 1991;33:403-8.
Smiles	CC(C1=C(CCN(C)C)CC2=C1C=CC=C2)C3=NC=CC=C3.O=C(O)/C=C\C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Endogenous Metabolite; Histamine Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	408.49
Product Description	Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions[1][2][3].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 125 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Clinical information	Launched

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HY-13710A-5mg-safety-datasheet.pdf