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CP-601932

CP-601932

Item no.	HY-138879B-10mg
Manufacturer	MedChem Express
CASRN	357425-68-4
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.74
Citations	[1]Chatterjee S, et al. Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats. Neuropsychopharmacology. 2011;36(3):603-615.
Smiles	FC(F)(C1=CC=C([C@@H]2C[C@H]3CNC2)C3=C1)F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	(1S,5R)-CP-601927
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	nAChR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	227.229
Product Description	CP-601932 ((1S, 5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 200 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Clinical information	No Development Reported

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HY-138879B-10mg-safety-datasheet.pdf