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PC Biotin-PEG3-azide

PC Biotin-PEG3-azide

Item no.	HY-140132-25mg
Manufacturer	MedChem Express
CASRN	1937270-46-6
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.25
Citations	[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Smiles	O=C(OC(C1=CC(OC)=C(OCCCC(NCCOCCOCCOCCNC(CCCC[C@H]2SC[C@@]([C@@]2([H])N3)([H])NC3=O)=O)=O)C=C1[N+]([O-])=O)C)NCCCN=[N+]=[N-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Cool pack
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	ADC Linker
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	825.93
Product Description	PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Manufacturer - Research Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related
Isoform	Cleavable Linker
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-140132-25mg-safety-datasheet.pdf