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Azido-PEG3-Val-Cit-PAB-PNP

Azido-PEG3-Val-Cit-PAB-PNP

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	50 mg
Item no.	HY-140150-50mg
Targets	ADC Linkers; PROTAC Linkers
CASRN	2055047-18-0
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG3-Val-Cit-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	773.79
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturers Target	ADC Linker; PROTAC Linkers
Isoform	Cleavable Linker; PEG Linkers; Protease Cleavable Linker
Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Manufacturers Product type	ADC Related

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