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Zileuton-d4

Zileuton-d4

Item no.	HY-14164S-1ea
Manufacturer	MedChem Express
CASRN	1189878-76-9
Amount	1 ea
Quantity options	1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.\|[2]Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10\|[3]Kuvibidila S, et al. Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease. Ochsner\|[4]Gounaris E, et al. Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation. PLoS One. 2015 Mar 6;10(3):e0121402
Smiles	ON(C([2H])(C1=CC2=CC=CC=C2S1)C([2H])([2H])[2H])C(N)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Ferroptosis; Isotope-Labeled Compounds; Lipoxygenase
Shipping Temperature	Room temperature
Molecular Weight	240.31
Product Description	Zileuton-d4 is the deuterium labeled Zileuton. Zileuton (A 64077) is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties[1][2].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Metabolic Enzyme/Protease; Others
Clinical information	No Development Reported

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