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SCP1-IN-1

SCP1-IN-1

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-142682-5mg
CASRN	2764615-55-4
Available
Product Description	SCP1-IN-1 (compound SH T-62) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-1 promotes REST degradation and reduces transcriptional activity. A high level of REST protein drives the tumor growth in some glioblastoma cells. SCP1-IN-1 has the potential for the research of glioblastoma whose growth is driven by REST transcription activity.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C20H19F3N2O7S2
References	[1].Medellin B, et al. Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. J Med Chem. 2022; 65(1):507-519.
MolecularWeight	520.5
Research Area	Cancer; Neurological Disease
Solubility	DMSO : 100 mg/mL (192.12 mM; Need ultrasonic)
Target	Others
Pathway	Others

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Amount: 5mg

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Delivery expected until 4/6/2023

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