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KRAS G12C inhibitor 23

KRAS G12C inhibitor 23

Item no.	HY-145020-100mg
Manufacturer	MedChem Express
CASRN	2735721-00-1
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Fused ring compound and application thereof in medicine. WO2021218939A1.
Smiles	O=C1N(C2=C(N=CC=C2C)C(C)C)C3=C(OCC4=CC=CC=C45)C5=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Ras
Shipping Temperature	Room temperature
Molecular Weight	553.63
Product Description	KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1)[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein; MAPK/ERK Pathway
Isoform	K-Ras
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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