« Back
Home /
KIF18A-IN-1

KIF18A-IN-1

Item no.	HY-145034-100mg
Manufacturer	MedChem Express
CASRN	2600559-12-2
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.39
Citations	[1]Pharmaceutical compositions comprising kinesin-like protein KIF18A inhibitors for the treatment of cancer. World Intellectual Property Organization, WO2023212714 A1 2023-11-02.\|[2]Payton M, et al. Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nat Cancer. 2024 Jan;5(1):66-84.
Smiles	O=C(C1=CC=C(S(=O)(NC(C)(C)C)=O)C=C1N2CCC3(CC3)CC2)NC4=CC=CC(S(=O)(NC(C)(C)C)=O)=C4
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Kinesin
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	576.77
Product Description	KIF18A-IN-1 is an inhibitor of the mitotic kinesin KIF18A with anti-tumor activity. KIF18A targeted inhibitors may activate mitotic checkpoints and selectively kill chromosomally unstable cancer cells[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Cytoskeleton
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-145034-100mg-safety-datasheet.pdf