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ADAMTS-5-IN-3

ADAMTS-5-IN-3

Item no.	HY-145061-5mg
Manufacturer	MedChem Express
CASRN	2688733-96-0
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.89
Citations	[1]Dong Liu, et al. Adamts inhibitors, preparation methods and medicinal uses thereof. WO2021158626A1.
Smiles	O=C(N1C[C@@H](C2=CC(Cl)=C(Cl)C=C2CC1)C)CC[C@]3(C4CC4)C(NC(N3)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	ADAMTS
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	424.32
Product Description	ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1].
Manufacturer - Research Area	Metabolic Disease; Inflammation/Immunology
Solubility	DMSO: 200 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-145061-5mg-safety-datasheet.pdf