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Dynole 2−24

Dynole 2−24

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	HY-145080-50mg
CASRN	1416313-72-8
Available
Product Description	Dynole 2−24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2−24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM). Dynole 2−24 also shows 4.4-fold selectivity for dynamin I. Dynole 2−24 is active in-cell inhibitor of clathrin-mediated endocytosis. CME: Clathrin mediated endocytosis
StorageTemperature	Please store the product under the recommended conditions in the Certificate of Analysis.
Applications	Neuroscience-Neuromodulation
Formula	C24H41N3
References	[1].Gordon CP, Venn-Brown B, Robertson MJ, et al. Development of second-generation indole-based dynamin GTPase inhibitors. J Med Chem. 2013; 56(1):46-59.
MolecularWeight	371.6
Research Area	Neurological Disease
Target	Dynamin
Pathway	Cytoskeleton

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 50mg

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Delivery expected until 4/13/2023

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