Comparison

ATR-IN-4 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50mg
Item no. HY-145312-50mg
CASRN 2574545-45-0
Available
Product Description
ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor. ATR-IN-4 inhibits growth of human prostate cancer cells DU145 and human lung cancer cells NCI-H460 with IC50s of 130.9 nM and 41 .33 nM, respectively. (Patent CN112142744A, compound 13).
StorageTemperature
4°C, sealed storage, away from moisture and light; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Applications
Cancer-Kinase/protease
Formula
C18H20N8O
References
[1].Substituted fused heteroaromatic bicyclic compounds as kinase inhibitors and uses thereof. CN112142744A.
MolecularWeight
364.4
Research Area
Cancer
Target
ATM/ATR
Pathway
Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 50mg
Available: In stock
available

Delivery expected until 4/6/2023 

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