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ATR-IN-4

ATR-IN-4

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	HY-145312-50mg
CASRN	2574545-45-0
Available
Product Description	ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor. ATR-IN-4 inhibits growth of human prostate cancer cells DU145 and human lung cancer cells NCI-H460 with IC50s of 130.9 nM and 41 .33 nM, respectively. (Patent CN112142744A, compound 13).
StorageTemperature	4°C, sealed storage, away from moisture and light; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Applications	Cancer-Kinase/protease
Formula	C18H20N8O
References	[1].Substituted fused heteroaromatic bicyclic compounds as kinase inhibitors and uses thereof. CN112142744A.
MolecularWeight	364.4
Research Area	Cancer
Target	ATM/ATR
Pathway	Cell Cycle/DNA Damage; PI3K/Akt/mTOR

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Amount: 50mg

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Delivery expected until 4/6/2023

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