Comparison

CDK5-IN-3 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 5mg
Item no. HY-145694-5mg
CASRN 2639542-32-6
Available
Product Description
CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD).
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications
Metabolism-protein/nucleotide metabolism
Formula
C22H26N4O
References
[1].Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022 Feb 24; 65(4):3575-3596.
MolecularWeight
362.47
Research Area
Metabolic Disease
Solubility
DMSO : 10 mg/mL (27.59 mM; Need ultrasonic)
Target
CDK
Isoform
Cdk5/p25; CDK2/CycA
Pathway
Cell Cycle/DNA Damage

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 5mg
Available: In stock
available

Delivery expected until 4/13/2023 

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