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CDK5-IN-3

CDK5-IN-3

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-145694-5mg
CASRN	2639542-32-6
Available
Product Description	CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD).
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Metabolism-protein/nucleotide metabolism
Formula	C22H26N4O
References	[1].Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022 Feb 24; 65(4):3575-3596.
MolecularWeight	362.47
Research Area	Metabolic Disease
Solubility	DMSO : 10 mg/mL (27.59 mM; Need ultrasonic)
Target	CDK
Isoform	Cdk5/p25; CDK2/CycA
Pathway	Cell Cycle/DNA Damage

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Amount: 5mg

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Delivery expected until 4/13/2023

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