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BAY-888

BAY-888

Item no.	HY-145939-50mg
Manufacturer	MedChem Express
CASRN	2468783-75-5
Amount	50 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.35
Formula	C28H26FN5O2
Citations	[1]Volker Schulze, et al. Substituted pyrrolo-pyridinone derivatives and therapeutic uses thereof. WO2022023337 A1. [2]Steven M. Corsello, et al Abstract 3588: Discovery of potent and selective CSNK1A1 inhibitors for solid tumor therapy. Cancer Res 15 June 2022; 82 (12_Supplement): 3588.
Smiles	O=C1C2=C(NC(C3=CC=NC(NC([C@@H](C)C4=CC=C(F)C=C4)=O)=C3)=C2NC5=CC=CC=C5)CCN1C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BRD5846
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Casein Kinase
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	483.54
Product Description	BAY-888 is an orally active CSNK1A1 and CSNK1D inhibitor with IC50 of 1.5 nM and 5.5 nM, respectively. BAY-888 has antitumor activity[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Stem Cell/Wnt
Clinical information	No Development Reported

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HY-145939-50mg-safety-datasheet.pdf