MPEP

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	250mg
Item no.	HY-14609A-250mg
CASRN	96206-92-7
Available
Product Description	MPEP is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Neuroscience-Neuromodulation
Formula	C14H11N
References	[1].F Gasparini, et al. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a Potent, Selective and Systemically Active mGlu5 Receptor Antagonist. Neuropharmacology. 1999 Oct; 38(10):1493-503. \| [2].E Tatarczyńska, et al. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. Br J Pharmacol. 2001 Apr; 132(7):1423-30.
MolecularWeight	193.24
Research Area	Neurological Disease
Target	mGluR
Isoform	mGluR5
Pathway	GPCR/G Protein; Neuronal Signaling

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Amount: 250mg

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Delivery expected until 4/6/2023

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