Comparison

MPEP European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 250mg
Item no. HY-14609A-250mg
CASRN 96206-92-7
Available
Product Description
MPEP is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects.
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications
Neuroscience-Neuromodulation
Formula
C14H11N
References
[1].F Gasparini, et al. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a Potent, Selective and Systemically Active mGlu5 Receptor Antagonist. Neuropharmacology. 1999 Oct; 38(10):1493-503. | [2].E Tatarczyńska, et al. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. Br J Pharmacol. 2001 Apr; 132(7):1423-30.
MolecularWeight
193.24
Research Area
Neurological Disease
Target
mGluR
Isoform
mGluR5
Pathway
GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 250mg
Available: In stock
available

Delivery expected until 4/6/2023 

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