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Glyoxalase I inhibitor 1

Glyoxalase I inhibitor 1

Item no.	HY-146653-100mg
Manufacturer	MedChem Express
CASRN	1622952-07-1
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Jin T, Zhao L, et al. Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem. 2020 Feb 15;28(4):115243.
Smiles	C#CCCCC(NC1=CC=C(C=C1)C(C2=CC=C(C=C2)NC3=NC=C(C(NC4=C(C=CC=C4)NS(C)(=O)=O)=N3)F)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Glyoxalase (GLO)
Shipping Temperature	Room temperature
Molecular Weight	586.64
Product Description	Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 26 nM[1]. Glyoxalase I inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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