Comparison

UCB-5307 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 10mg
Item no. HY-147045-10mg
CASRN 1515887-44-1
Available
Product Description
UCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex.
StorageTemperature
4°C, sealed storage, away from moisture and light; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Applications
COVID-19-immunoregulation
Formula
C22H21N3O
References
[1].O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19; 10(1):5795.
MolecularWeight
343.42
Research Area
Inflammation/Immunology
Solubility
DMSO : 50 mg/mL (145.59 mM; Need ultrasonic)
Target
TNF Receptor
Pathway
Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 10mg
Available: In stock
available

Delivery expected until 4/20/2023 

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