Comparison

MSC-4106 European Partner

Item no. HY-147208-5mg
Manufacturer MedChem Express
CASRN 2738542-58-8
Amount 5 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.82
Formula C18H12F3N3O2
Citations [1]Timo Heinrich, et al. Optimization of TEAD P-site binding fragment hit into in vivo active lead MSC-4106. J. Med. Chem. 2022, 65, 13, 9206–9229.
Smiles O=C(C1=CC2=C(N(C3=CC=C(C(F)(F)F)C=C3)C4=NN(C)C=C42)C=C1)O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping condition Cool pack
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
YAP
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Molecular Weight
359.30
Product Description
MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model[1].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 250 mg/mL (ultrasonic)
Manufacturer - Pathway
Stem Cell/Wnt
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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