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Odetiglucan

Odetiglucan

Item no.	HY-147295-1ea
Manufacturer	MedChem Express
CASRN	53238-80-5
Amount	1 ea
Quantity options	100 mg 1 ea 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Citations	[1]WHO Drug Information. International Nonproprietary Names for Pharmaceutical\|[2]Stacy K Thomas, et al. Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice. Nat Commun. 2023 Oct 10;14(1):6330.
Smiles	OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O[H])[C@H](O)[C@@H](CO)O3)[C@H](O)[C@@H](CC[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O[H])[C@H]4O)O2)[C@@H]1O.[x].[y].[x=y~10;z~4;n~4;(x+y+z+1)x n~100].[(C6H10O5)n(H2O);n=100;M=16 kDa].[z]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BTH 1677,Imprime PGG
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Toll-like Receptor (TLR)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Product Description	Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response[1][2].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO: 100 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	Phase 1

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HY-147295-1ea-safety-datasheet.pdf