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NOD2 antagonist 1

NOD2 antagonist 1

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10 mg
Item no.	HY-147506-10mg
CASRN	2411441-54-6
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP)-induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-α release in PBMCs[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	474.57
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturers Target	NOD-like Receptor (NLR)
Isoform	NOD2
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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