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NOD2 antagonist 1

NOD2 antagonist 1

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	10mg
Item no.	HY-147506-10mg
CASRN	2411441-54-6
Available
Product Description	NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP)-induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-α release in PBMCs.
StorageTemperature	Please store the product under the recommended conditions in the Certificate of Analysis.
Applications	COVID-19-immunoregulation
Formula	C26H26N4O3S
References	[1].Guzelj S, et al. Structural features and functional activities of benzimidazoles as NOD2 antagonists. Eur J Med Chem. 2020; 190:112089.
MolecularWeight	474.57
Research Area	Inflammation/Immunology
Target	NOD-like Receptor (NLR)
Isoform	NOD2
Pathway	Immunology/Inflammation

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Amount: 10mg

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Delivery expected until 4/13/2023

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