QN523

Item no.	HY-148255-100mg
Manufacturer	MedChem Express
CASRN	878581-60-3
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.77
Citations	[1]Kuang Y, et, al. Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. J Med Chem. 2022 Apr 28;65(8):6133-6156.\|[2]Kuang Y, et, al. Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. J Med Chem. 2022 Apr 28;65(8):6133-6156.
Smiles	O=C(C1=NC=CN=C1)NC2=CC=CC3=CC=CN=C32
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Autophagy
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	250.26
Product Description	QN523 is a novel scaffold with agent-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 induces apoptosis and autophagy. QN523 can be used in research of cancer[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 16.67 mg/mL
Manufacturer - Pathway	Apoptosis; Autophagy
Clinical information	No Development Reported

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HY-148255-100mg-safety-datasheet.pdf