HKB99

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Amount	1 ea
Item no.	HY-148510-1ea
CASRN	2414908-90-8
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 inhibits the formation of invasive pseudopodia and increases the level of PAI-2 in vitro. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
MolecularWeight	450.46
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturers Target	Phosphatase
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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