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Topoisomerase I/II inhibitor 4

Topoisomerase I/II inhibitor 4

Item no.	HY-149002-100mg
Manufacturer	MedChem Express
CASRN	3031403-77-4
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Yang X, et al. Optimization of the Natural Product Calothrixin A to Discover Novel Dual Topoisomerase I and II Inhibitors with Improved Anticancer Activity. J Med Chem. 2022 Jun 9;65(11):8040-8061.
Smiles	O=C1C2=C(C(C3=C1C4=C(C=CC=C4)N3CC5=CN([C@H]6O[C@@H]([C@H](C6)O)CO)N=N5)=O)C7=C([N+]([O-])=C2)C=CC=C7
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Topoisomerase
Shipping Temperature	Room temperature
Molecular Weight	511.49
Product Description	Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Cell Cycle/DNA Damage
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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