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Nemonoxacin-d3-1

Nemonoxacin-d3-1

Item no.	HY-14956S1-1ea
Manufacturer	MedChem Express
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Citations	[1]Adam HJ, et al. In vitro activity of nemonoxacin, a novel nonfluorinated quinolone, against 2,440 clinical isolates. Antimicrob Agents Chemother. 2009 Nov;53(11):4915-20. [2]Li CR, et al. In vivo antibacterial activity of nemonoxacin, a novel non-fluorinated quinolone. J Antimicrob Chemother. 2010 Nov;65(11):2411-5. [3]Lauderdale TL, et al. Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates. Antimicrob Agents Chemother. 2010 Mar;54(3):1338-42. [4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
Smiles	O=C(C1=CN(C2CC2)C3=C(C=CC(N4C[C@@H](N)C[C@H](C([2H])([2H])[2H])C4)=C3OC)C1=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TG-873870-d3-1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial
Shipping Temperature	Room temperature
Molecular Weight	374.45
Product Description	Nemonoxacin-d3-1 is the deuterium labeled Nemonoxacin. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia[1][2][3].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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