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AKT inhibitor IV

AKT inhibitor IV

Item no.	HY-14971A-1mg
Manufacturer	MedChem Express
CASRN	681281-88-9
Amount	1 mg
Quantity options	1 ea 1 mg
Category	Food Safety Banned Food Additives Contaminants Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.40
Citations	[1]Changkun Hu, et al. A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells. Eur J Med Chem. 2010 Feb;45(2):705-9.
Smiles	CN(/C=C/C1=[N+](C2=CC=CC=C2)C3=CC=C(C4=NC5=CC=CC=C5S4)C=C3N1CC)C6=CC=CC=C6.[I-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AKTIV
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Category	Reference compound / Active compounds
Manufacturer - Targets	Akt
Manufacturer - HS Code	H315, H319, H335
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	614.54
Product Description	Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	PI3K/Akt/mTOR
Clinical information	Phase 4
UNSPSC Code	12352005
Precautionary	H315, H319, H335

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