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MLKL-IN-3

MLKL-IN-3

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Amount	1 ea
Item no.	HY-151541-1ea
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	MLKL-IN-3 (compound 66) is a potent MLKL (Mixed lineage kinase domain-like protein) inhibitor. MLKL-IN-3 inhibits necroptosis in HT-29 cells and acts downstream of MLKL phosphorylation, with EC50 of 31 nM[1]. MLKL-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	589.04
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturers Target	Mixed Lineage Kinase; Necroptosis
Pathway	Apoptosis; MAPK/ERK Pathway
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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