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Epothilone D

Epothilone D

Item no.	HY-15278-100mg
Manufacturer	MedChem Express
CASRN	189453-10-9
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.93
Citations	[1]Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.\|[2]Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6.
Smiles	O=C(O[C@@H](C/C=C(CCC[C@@H]([C@@H]([C@H](C1=O)C)O)C)/C)/C(C)=C/C2=CSC(C)=N2)C[C@@H](C1(C)C)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	KOS 862
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Antibiotic; Bacterial; Fungal; Microtubule/Tubulin
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	491.68
Product Description	Epothilone D (KOS 862) is a potent microtubule stabilizer.
Manufacturer - Research Area	Cancer; Infection
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage; Cytoskeleton
Clinical information	Phase 2

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HY-15278-100mg-safety-datasheet.pdf