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Cabergoline-d5

Cabergoline-d5

Item no.	HY-15296S-2.5mg
Manufacturer	MedChem Express
CASRN	1426173-20-7
Amount	2.5 mg
Quantity options	2.5 mg 250 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271.\|[3]Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21.
Smiles	[2H]/C([2H])=C([2H])\C([2H])([2H])N1[C@@]2([H])[C@@](C[C@H](C1)C(N(CCCN(C)C)C(NCC)=O)=O)([H])C3=CC=CC4=C3C(C2)=CN4
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	FCE-21336-d5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Autophagy; Dopamine Receptor; Isotope-Labeled Compounds
Shipping Temperature	Room temperature
Molecular Weight	456.64
Product Description	Cabergoline-d5 is the deuterium labeled Cabergoline. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively)[1][2].
Manufacturer - Research Area	Endocrinology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Isoform	5-HT2 Receptor; D2 Receptor; D3 Receptor
Clinical information	No Development Reported

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