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8-OH-DPAT (hydrobromide)

8-OH-DPAT (hydrobromide)

Item no.	HY-15688-10mg
Manufacturer	MedChem Express
CASRN	76135-31-4
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.89
Formula	C16H26BrNO
Citations	Eur J Pharmacol. 2023 Oct 21:176147. Nature. 2024 Jun;630(8015):237-246. [1]D N Middlemiss, et al. 8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT<sub>1 </sub> recognition site. Eur J Pharmacol. 1983 May 20;90(1):151-3. [2]Michael A Taffe, et al. Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge. Neuropsychopharmacology. 2002 Dec;27(6):993-1005.
Smiles	OC1=C2CC(N(CCC)CCC)CCC2=CC=C1.[H]Br
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	8-Hydroxy-DPAT (hydrobromide)
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	5-HT Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	328.29
Product Description	8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : 25 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	5-HT1 Receptor
Clinical information	No Development Reported

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HY-15688-10mg-safety-datasheet.pdf