« Back
Home /
NB-598 Maleate

NB-598 Maleate

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	100mg
Item no.	HY-16343C-100mg
CASRN	155294-62-5
Available
Product Description	NB-598 Maleate is a potent and competitive inhibitor of squalene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway.
StorageTemperature	4°C, stored under nitrogen; In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Applications	Metabolism-sugar/lipid metabolism
Formula	C31H35NO5S2
References	[1].Xia F, et al. Inhibition of cholesterol biosynthesis impairs secretion and voltage-gated calcium channel function in pancreatic beta-cells. Endocrinology. 2008 Oct; 149(10):5136-45. \| [2].Horie M, et al. Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells. Biochem Pharmacol. 1993 Jul 20; 46(2):297-305. \| [3].Horie M, et al. An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. Biochim Biophys Acta. 1993 May 20; 1168(1):45-51.
MolecularWeight	565.74
Research Area	Metabolic Disease
Solubility	DMSO : 100 mg/mL (176.76 mM; Need ultrasonic)
Target	Others
Pathway	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100mg

available

Delivery expected until 4/20/2023

Compare

Add to wishlist

Recommend by mail

Request delivery time

Ask a technical question