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PG-11047 (tetrahydrochloride)

PG-11047 (tetrahydrochloride)

Item no.	HY-16394-50mg
Manufacturer	MedChem Express
CASRN	206991-64-2
Amount	50 mg
Quantity options	10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Wen-Lin Kuo, et al. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009 Dec 14;7:77.\|[2]Murray Stewart T, et al. A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. Cancer Chemother Pharmacol. 2021 Jan;87(1):135-144.
Smiles	CCNCCCNC/C=C\CNCCCNCC.[H]Cl.[H]Cl.[H]Cl.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CGC-11047 (tetrahydrochloride)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Drug Derivative
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	402.27
Product Description	PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO\|H2O: ≥ 30 mg/mL
Manufacturer - Pathway	Others
Clinical information	Phase 2

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HY-16394-50mg-safety-datasheet.pdf