Comparison

Pamabrom European Partner

Item no. HY-17391-50mg
Manufacturer MedChem Express
CASRN 606-04-2
Amount 50 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.92
Citations [1]Ortiz MI, et al. Effect of nitric oxide-cyclic GMP-K+ channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom. Can J Physiol Pharmacol. 2023 Jan 1;101 (1) :41-51.
Smiles O=C(N1C)N(C)C2=C(N=C(Br)N2)C1=O.CC(C)(N)CO
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Neuroscience-Neuromodulation
Manufacturer - Targets
Adenosine Receptor
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
348.201
Product Description
Pamabrom is a diuretic that acts on the opioid receptor-nitric oxide (NO) -cyclic guanosine monophosphate (cGMP) -K+ channel pathway. Pamabrom exerts peripheral antinociceptive activity by activating this pathway. The mechanism involves activating opioid receptors, promoting the release of nitric oxide, and then influencing cyclic guanosine monophosphate and K channels to produce an analgesic effect. Pamabrom is orally active and is mainly used in the research and treatment of premenstrual syndrome and primary dysmenorrhea[1].
Manufacturer - Research Area
Endocrinology
Solubility
DMSO: 150 mg/mL (ultrasonic)
Manufacturer - Pathway
GPCR/G Protein
Clinical information
Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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