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Tesaglitazar

Tesaglitazar

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	10mg
Item no.	HY-17444-10mg
CASRN	251565-85-2
Available
Product Description	Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively, and approximately 0.2 μM for both rat and human PPARγ. Tesaglitazar induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats.
StorageTemperature	-20°C, sealed storage, away from moisture; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Applications	Neuroscience-Neuromodulation
Formula	C20H24O7S
References	[1].Hellmold H, et al. Tesaglitazar, a PPARalpha/gamma agonist, induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats. Toxicol Sci. 2007 Jul; 98(1):63-74.
MolecularWeight	408.47
Research Area	Cancer; Metabolic Disease
Solubility	DMSO : 200 mg/mL (489.63 mM; ultrasonic and warming and heat to 60°C)
Target	PPAR
Pathway	Cell Cycle/DNA Damage

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Amount: 10mg

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Delivery expected until 4/20/2023

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