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sn-Glycero-3-phosphocholine

sn-Glycero-3-phosphocholine

Item no.	HY-17552-500mg
Manufacturer	MedChem Express
CASRN	28319-77-9
Amount	500 mg
Quantity options	10 g 10 mM/1 mL 1 g 25 g 500 mg 50 g 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Lee SH, et al. Late treatment with choline alfoscerate (l-alpha glycerylphosphorylcholine, α-GPC) increases hippocampal neurogenesis and provides protection against seizure-induced neuronal death and cognitive impairment. Brain Res. 2017 Jan 1;1654(Pt A):66-76.\|[2]Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipidwith a still interesting profile as cognition enhancing agent. Curr Alzheimer Res. 2013 Dec;10(10):1070-9.
Smiles	O=P(OCC[N+](C)(C)C)(OC[C@H](O)CO)[O-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Choline Alfoscerate,Alpha-GPC,L-α-GPC
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Cholinesterase (ChE); Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen, away from moisture)
Molecular Weight	257.22
Product Description	sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	Human Endogenous Metabolite
Clinical information	Launched

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HY-17552-500mg-safety-datasheet.pdf