Comparison

BI-9627 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 10 mg
Item no. HY-18071-10mg
CASRN 1204329-34-9
eClass 6.1 30220300
eClass 9.0 32160605
Available
Product Description
BI-9627 is potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC50s of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively. BI-9627 displays >30-fold selectivity against NHE2 and with no measurable inhibitory activity against the NHE3 isoform. BI-9627 shows low DDI (agent-agent interaction) potential, excellent pharmacokinetics in rat and dog, and remarkably potent activity in the isolated heart model of ischemia-reperfusion injury[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Neuroscience-Neuromodulation
Molecular Weight
356.34
Clinical Information
No Development Reported
Solubility
DMSO : 100 mg/mL (ultrasonic)
Pathway
Membrane Transporter/Ion Channel
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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