Comparison

KU 59403 European Partner

Item no. HY-18650-5mg
Manufacturer MedChem Express
CASRN 845932-30-1
Amount 5 mg
Quantity options 10 mg 1 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.23
Formula C29H32N4O4S2
Citations [1]Batey MA, et al. Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer. Mol Cancer Ther. 2013 Jun;12(6):959-67.
Smiles O=C(NC(C=C1S2)=CC=C1SC3=C2C=CC=C3C4=CC(C=C(N5CCOCC5)O4)=O)CCN6CCN(C)CC6
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping condition Cool pack
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-Kinase/protease
Manufacturer - Targets
ATM/ATR
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Molecular Weight
564.72
Product Description
KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively[1].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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