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Amelubant

Amelubant

Item no.	HY-19304-50mg
Manufacturer	MedChem Express
CASRN	346735-24-8
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.11
Formula	C33H34N2O5
Citations	[1]Birke FW, et al. In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist. J Pharmacol Exp Ther. 2001 Apr;297(1):458-66.
Smiles	CC(C1=CC=C(OCC2=CC(COC3=CC=C(C(NC(OCC)=O)=N)C=C3)=CC=C2)C=C1)(C4=CC=C(O)C=C4)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BIIL 284
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Leukotriene Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	538.63
Product Description	Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes. Amelubant (BIIL 284) is a proagent of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein
Isoform	LTB4
Clinical information	Phase 2

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HY-19304-50mg-safety-datasheet.pdf