Comparison

cis-4-Hydroxy-L-proline European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 100mg
Item no. HY-40136-100mg
CASRN 618-27-9
Available
Product Description
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors.
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications
Metabolism-protein/nucleotide metabolism
Formula
C5H9NO3
References
[1].Lewko WM, et, al. Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res. 1981 Jul; 41(7):2855-62. | [2].Kao WW, et, al. Proline analogue removes fibroblasts from cultured mixed cell populations. Nature. 1977 Mar 3; 266(5597):63-4. | [3].Tan EM, et, al. Proline analogues inhibit human skin fibroblast growth and collagen production in culture. J Invest Dermatol. 1983 Apr; 80(4):261-7. | [4].Riley DJ, et, al. Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-l-proline. Am Rev Respir Dis. 1981 Apr; 123(4 Pt 1):388-93.
MolecularWeight
131.13
Research Area
Cancer; Metabolic Disease
Solubility
H2O : 100 mg/mL (762.60 mM; Need ultrasonic) | DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) (insoluble or slightly soluble)
Target
Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 100mg
Available: In stock
available

Delivery expected until 4/13/2023 

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