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IRAK-4 protein kinase inhibitor 2

IRAK-4 protein kinase inhibitor 2

Item no.	HY-77048-10mg
Manufacturer	MedChem Express
CASRN	301675-24-1
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 5 mg
Category	Oncology By Cell Type Hematology Leukemia Lymphoma Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.01
Formula	C14H10N4O3
Citations	[1]Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.
Smiles	O=C(NC1=NC2=CC=CC=C2N1)C3=CC=CC([N+]([O-])=O)=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	301675-24-1
Similar products	301675-24-1
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	IRAK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	282.25
Product Description	IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disorders[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO : 10 mg/mL (ultrasonic)
Manufacturer - Pathway	Immunology/Inflammation
Isoform	IRAK4
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-77048-10mg-safety-datasheet.pdf