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Succinic anhydride-d4

Succinic anhydride-d4

Item no.	HY-79369S-1g
Manufacturer	MedChem Express
CASRN	14341-86-7
Amount	1 g
Quantity options	100 mg 1 ea 1 g 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1.
Smiles	O=C1OC(C([2H])([2H])C1([2H])[2H])=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	ADC Linker; Isotope-Labeled Compounds
Shipping Temperature	Room temperature
Molecular Weight	104.10
Product Description	Succinic anhydride-d4 is the deuterium labeled Succinic anhydride. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Others
Clinical information	No Development Reported

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