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Capecitabine-d11

Capecitabine-d11

Item no.	HY-B0016S-1ea
Manufacturer	MedChem Express
CASRN	1132662-08-8
Amount	1 ea
Quantity options	1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.\|[2]PharmD CM, et al. Capecitabine: A review. Clinical Therapeutics. 2005 Jan; 27(1): 23-44.\|[3]Guichard SM, et al. Gene expression predicts differential capecitabine metabolism, impacting on both pharmacokinetics and antitumour activity. Eur J Cancer. 2008 Jan;44(2):310-7.
Smiles	C[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C(F)=C2)NC(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)=O)O1)O)O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; DNA/RNA Synthesis; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	370.42
Product Description	Capecitabine-d11 is the deuterium labeled Capecitabine. Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 250 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Apoptosis; Cell Cycle/DNA Damage; Others
Clinical information	No Development Reported

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HY-B0016S-1ea-safety-datasheet.pdf