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Nimodipine-d7

Nimodipine-d7

Item no.	HY-B0265S-10mg
Manufacturer	MedChem Express
CASRN	1246815-36-0
Amount	10 mg
Quantity options	10 mg 1 mg 2 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.35
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Langley, M.S., et al. Nimodipine. Drugs 37, 669–699 (1989).\|[3] Marbacher S, et al. Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo. Intensive Care Med. 2008;34(5):932-938.\|[4]Honn KV, et al. Inhibition of tumor cell-platelet interactions and tumor metastasis by the calcium channel blocker, nimodipine. Clin Exp Metastasis. 1984;2(1):61-72.
Smiles	O=C(C1=C(C)NC(C)=C(C(OC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCCOC
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Autophagy; Calcium Channel; Isotope-Labeled Compounds
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	425.48
Product Description	Nimodipine-d7 is the deuterium labeled Nimodipine. Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders[1].
Manufacturer - Research Area	Cardiovascular Disease; Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Clinical information	No Development Reported

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Amount: 10 mg

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