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Pyrazinamide

Pyrazinamide

Item no.	HY-B0271-500mg
Manufacturer	MedChem Express
CASRN	98-96-4
Amount	500 mg
Quantity options	10 g 10 mM/1 mL 500 mg 50 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.97
Citations	[1]Y Zhang, et al. Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide. J Bacteriol. 1999 Apr;181(7):2044-9.\|[2]Ying Zhang, et al. Mechanisms of Pyrazinamide Action and Resistance. Microbiol Spectr. 2014 Aug;2(4):MGM2-0023-2013.
Smiles	O=C(C1=NC=CN=C1)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Pyrazinecarboxamide,Pyrazinoic acid amide
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Autophagy; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	Store at room temperature 3 years
Molecular Weight	123.11
Product Description	Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
Manufacturer - Research Area	Infection
Solubility	DMSO: ≥ 50 mg/mL\|H2O: 6.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Autophagy
Clinical information	Launched

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HY-B0271-500mg-safety-datasheet.pdf