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Urapidil hydrochloride

Urapidil hydrochloride

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	HY-B0354A-50mg
CASRN	64887-14-5
Available
Product Description	Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist with a pIC50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect.
StorageTemperature	4°C, sealed storage, away from moisture; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Applications	COVID-19-immunoregulation
Formula	C20H30ClN5O3
References	[1].Gross, G., G. Hanft, and N. Kolassa, Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for alpha 1-adrenoceptor binding sites. Naunyn Schmiedebergs Arch Pharmacol, 1987. 336(6): p. 597-601. \| [2].Buch, J., Urapidil, a dual-acting antihypertensive agent: Current usage considerations. Adv Ther, 2010. 27(7): p. 426-43.
MolecularWeight	423.94
Research Area	Cardiovascular Disease; Endocrinology
Solubility	H2O : 100 mg/mL (235.88 mM; Need ultrasonic) \| DMSO : 14.29 mg/mL (33.71 mM; ultrasonic and warming and heat to 60°C)
Target	5-HT Receptor; Adrenergic Receptor
Isoform	5-HT1A Receptor; α1-adrenergic receptor; α2-adrenergic receptor
Pathway	GPCR/G Protein; Neuronal Signaling

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Amount: 50mg

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Delivery expected until 4/13/2023

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