Comparison

Urapidil hydrochloride European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50mg
Item no. HY-B0354A-50mg
CASRN 64887-14-5
Available
Product Description
Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist with a pIC50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect.
StorageTemperature
4°C, sealed storage, away from moisture; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Applications
COVID-19-immunoregulation
Formula
C20H30ClN5O3
References
[1].Gross, G., G. Hanft, and N. Kolassa, Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for alpha 1-adrenoceptor binding sites. Naunyn Schmiedebergs Arch Pharmacol, 1987. 336(6): p. 597-601. | [2].Buch, J., Urapidil, a dual-acting antihypertensive agent: Current usage considerations. Adv Ther, 2010. 27(7): p. 426-43.
MolecularWeight
423.94
Research Area
Cardiovascular Disease; Endocrinology
Solubility
H2O : 100 mg/mL (235.88 mM; Need ultrasonic) | DMSO : 14.29 mg/mL (33.71 mM; ultrasonic and warming and heat to 60°C)
Target
5-HT Receptor; Adrenergic Receptor
Isoform
5-HT1A Receptor; α1-adrenergic receptor; α2-adrenergic receptor
Pathway
GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 50mg
Available: In stock
available

Delivery expected until 4/13/2023 

Compare

Add to wishlist

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close